SCHEMBL2844906

SCHEMBL2844906

O=C1OC2(c3ccccc31)c1cc([N+](=O)[O-])c(O)c(Br)c1Oc1c2cc([N+](=O)[O-])c(O)c1Br

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 2/20 0.70
TDP1 Q9NUW8 5/20 0.54
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
RECQL P46063 3/20 0.54
BLM P54132 2/20 0.54
ACE2 Q9BYF1 2/20 0.54
THRB P10828 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
USP2 O75604 2/20 0.54
CDK2 P24941 1/20 0.54
CHAT P28329 1/20 0.54
BLVRB P30043 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
GNG2 P59768 1/20 0.52
GNB1 P62873 1/20 0.52
AKR1C1 Q04828 1/20 0.50
HSP90AA1 P07900 2/20 0.47
MAPT P10636 6/20 0.46
FTO Q9C0B1 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2681408 1.00 PRMT1 (0.70) PRMT1TDP1MEN1KMT2ARECQL
SCHEMBL31292282 1.00 PRMT1 (0.70) PRMT1TDP1MEN1KMT2ARECQL
SCHEMBL7856216 0.99 PRMT1 (0.69) PRMT1TDP1MEN1KMT2ARECQL
SCHEMBL17278439 0.91 PRMT1 (0.59) PRMT1TDP1MEN1KMT2ARECQL
SCHEMBL9474670 0.88 PRMT1 (0.55) PRMT1TDP1MEN1KMT2ARECQL
SCHEMBL5886228 0.86 MEN1 (0.54) PRMT1TDP1MEN1KMT2ARECQL
SCHEMBL28388860 0.86 PRMT1 (0.57) PRMT1TDP1MEN1KMT2ARECQL
SCHEMBL29379413 0.86 PRMT1 (0.57) PRMT1TDP1MEN1KMT2ARECQL
SCHEMBL11056465 0.85 PRMT1 (0.51) PRMT1TDP1MEN1KMT2ARECQL
Eosin SCHEMBL29350830 0.83 PRMT1 (1.00) PRMT1TDP1MEN1KMT2ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10589003-B2 Methods for coating surfaces with antimicrobial agents THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2020-03-17 US disclosed
US-20180303977-A1 METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2018-10-25 US disclosed
US-8647885-B2 Process for detecting gaseous halogenated compounds COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2014-02-11 US disclosed
US-20100136704-A1 Process for Detecting Gaseous Halogenated Compounds CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2010-06-03 US disclosed
US-7713472-B2 Antiseptic derivatives with broad spectrum antimicrobial activity for the impregnation of surfaces BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-05-11 US disclosed
US-7651661-B2 Medical devices with broad spectrum antimicrobial activity BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-01-26 US disclosed
EP-2145179-A2 PROCESS FOR DETECTING GASEOUS HALOGENATED COMPOUNDS Commissariat à l'Energie Atomique (FR) 2010-01-20 EP disclosed
WO-2008148987-A2 PROCESS FOR DETECTING GASEOUS HALOGENATED COMPOUNDS COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2008-12-11 WO disclosed
US-20080183152-A1 MEDICAL DEVICES WITH BROAD SPECTRUM ANTIMICROBIAL ACTIVITY RAAD ISSAM 2008-07-31 US disclosed
US-20070154621-A1 METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2007-07-05 US disclosed
US-20050197634-A1 Methods for coating and impregnating medical devices with antiseptic compositions BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2005-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10589003-B2 Methods for coating surfaces with antimicrobial agents CUTA, CD63, CDC37 PRMT1 1021/4885TDP1 4002/4885MEN1 4111/4885
US-20180303977-A1 METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS CUTA, CD63, CDC37 PRMT1 1021/4885TDP1 4002/4885MEN1 4111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.