Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | CHAT | P28329 | 1/20 | 0.54 |
| ▸ | BLVRB | P30043 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | GNG2 | P59768 | 1/20 | 0.52 |
| ▸ | GNB1 | P62873 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844906 | 0.86 | PRMT1 (0.70) | MEN1KMT2ATDP1RECQLBLM | |
| SCHEMBL2681408 | 0.86 | PRMT1 (0.70) | MEN1KMT2ATDP1RECQLBLM | |
| SCHEMBL31292282 | 0.86 | PRMT1 (0.70) | MEN1KMT2ATDP1RECQLBLM | |
| SCHEMBL7856216 | 0.85 | PRMT1 (0.69) | MEN1KMT2ATDP1RECQLBLM | |
| SCHEMBL14750826 | 0.83 | MEN1 (0.61) | MEN1KMT2ATDP1RECQLBLM | |
| SCHEMBL25113777 | 0.81 | MEN1 (0.77) | MEN1KMT2ATDP1RECQLBLM | |
| SCHEMBL5886179 | 0.81 | MEN1 (0.58) | MEN1KMT2ATDP1RECQLBLM | |
| SCHEMBL4960577 | 0.80 | MAPT (0.62) | MEN1KMT2ATDP1RECQLBLM | |
| SCHEMBL17278439 | 0.78 | PRMT1 (0.59) | MEN1KMT2ATDP1RECQLBLM | |
| SCHEMBL4201826 | 0.77 | MAPT (0.59) | MEN1KMT2ATDP1RECQLBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041821-B2 | substituted 3-hydroxy-6-oxo-9-phenyl anthracene, acridine, xanthene, or thioxanthene zinc chelating compounds; fluorescent labels for recombinant fusion proteins; nontoxic alternative to nickel based labeling systems; nonreducing environments, cell surfaces | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-05-09 | — | — | US | disclosed |
| US-6933384-B2 | Synthetic molecules for labeling histidine-rich proteins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-08-23 | — | — | US | disclosed |
| US-20040241749-A1 | Synthetic molecules for labeling histidine-rich proteins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-12-02 | — | — | US | disclosed |
| US-20040143122-A1 | Synthetic molecules for labeling histidine-rich proteins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040143122-A1 | Synthetic molecules for labeling histidine-rich proteins | SLC39A14, SLC39A3, SLC30A6 | MEN1 2204/4885KMT2A 2029/4885TDP1 4287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.