Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD5 | P21918 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28456966 | 0.81 | OPRD1 (0.37) | KMT2AOPRD1HHATDRD1DRD2 | |
| SCHEMBL28446844 | 0.81 | OPRD1 (0.37) | KMT2AOPRD1HHATDRD1DRD2 | |
| SCHEMBL28449410 | 0.79 | OPRD1 (0.38) | OPRD1HHAT | |
| SCHEMBL29970949 | 0.76 | DRD1 (0.59) | KMT2AHHATDRD1 | |
| SCHEMBL28681399 | 0.76 | HHAT (0.46) | OPRD1HHATDRD1DRD2DRD4 | |
| SCHEMBL3303648 | 0.75 | MAOA (0.42) | DRD1DRD2DRD4DRD5DRD3 | |
| SCHEMBL29271775 | 0.75 | TRPV1 (0.44) | HHAT | |
| SCHEMBL28449413 | 0.73 | SMN1; SMN2 (0.36) | KMT2ADRD1 | |
| SCHEMBL28459877 | 0.72 | SMN1; SMN2 (0.35) | KMT2A | |
| SCHEMBL21465733 | 0.71 | DRD1 (0.60) | HHATDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922430-B | 2-substituted benzimidazole-4-formamide compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2020-09-04 | — | — | CN | disclosed |