Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400520 | 0.85 | HPGD (0.48) | HPGDMT-CO2PTGS2PTGS1KMT2A | |
| SCHEMBL14864467 | 0.84 | HPGD (0.50) | HPGDMT-CO2PTGS2PTGS1KMT2A | |
| SCHEMBL17086711 | 0.84 | HPGD (0.50) | HPGDMT-CO2PTGS2PTGS1KMT2A | |
| SCHEMBL2170797 | 0.84 | HPGD (0.50) | HPGDMT-CO2PTGS2PTGS1KMT2A | |
| SCHEMBL12896284 | 0.83 | HPGD (0.53) | HPGDMT-CO2PTGS2PTGS1KMT2A | |
| SCHEMBL11130803 | 0.83 | HPGD (0.53) | HPGDMT-CO2PTGS2PTGS1KMT2A | |
| SCHEMBL17073087 | 0.82 | HPGD (0.46) | HPGDMT-CO2PTGS2PTGS1KMT2A | |
| SCHEMBL11014337 | 0.82 | ALOX15 (0.49) | HPGDMT-CO2PTGS2PTGS1KMT2A | |
| SCHEMBL1747458 | 0.82 | ESR1 (0.56) | HPGDMT-CO2PTGS2PTGS1KMT2A | |
| SCHEMBL12424105 | 0.82 | HPGD (0.51) | HPGDMT-CO2PTGS2PTGS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574322-A | Preparation method of difluoromethyl aromatic compound | 南京工业大学 | 2020-08-25 | — | — | CN | disclosed |