SCHEMBL2844943

SCHEMBL2844943

COc1cc(Br)c(S(=O)(=O)O)cc1Br

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
PRKDC P78527 1/20 0.44
LCK P06239 2/20 0.43
FYN P06241 1/20 0.43
ERN1 O75460 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
GRIN2B Q13224 1/20 0.42
GRIN2C Q14957 1/20 0.42
GRIN3A Q8TCU5 1/20 0.42
MAPT P10636 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALPL P05186 1/20 0.40
POLB P06746 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2838080 0.92 TSHR (0.47) TSHRPRKDCLCKFYNERN1
SCHEMBL4347833 0.81 CA1 (0.40) TSHRLCKFYNALDH1A1SMN1; SMN2
SCHEMBL18726107 0.78 TSHR (0.60) TSHRPRKDCLCKFYNERN1
SCHEMBL11871669 0.77 CA1 (0.42) TSHRLCKFYNALDH1A1POLB
Water SCHEMBL7908328 0.77 TSHR (0.59) TSHRPRKDCLCKFYNERN1
SCHEMBL298224 0.76 POLB (0.59) PRKDCGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL25046087 0.75 SMN1; SMN2 (0.47) TSHRALDH1A1MAPTTAAR1SMN1; SMN2
SCHEMBL1888725 0.74 ALDH1A1 (0.51) TSHRALDH1A1MAPTHTR2ASMN1; SMN2
SCHEMBL5082288 0.74 CA1 (0.41) TSHRALDH1A1POLBLMNAL3MBTL1
SCHEMBL31172608 0.74 PKM (0.61) TSHRPRKDCGRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120251919-A1 POLYARYLENE-BASED COPOLYMER AND USES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 US disclosed
EP-2489690-A1 POLYARYLENE COPOLYMER AND USES THEREOF Sumitomo Chemical Company Limited (JP) 2012-08-22 EP disclosed
US-20100129729-A1 CEOSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE,CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL SUMITOMO CHEMICAL COMPANY ,LIMITED 2010-05-27 US disclosed
EP-2147943-A1 CROSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE, CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL Sumitomo Chemical Company, Limited (JP) 2010-01-27 EP disclosed
US-20090253015-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) 2009-10-08 US disclosed
EP-1857482-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2007-11-21 EP disclosed