SCHEMBL28449487

SCHEMBL28449487

c1cc2c(cnc3ccoc32)o1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35
NFKB1 P19838 1/20 0.35
DYRK1A Q13627 1/20 0.33
HTR2C P28335 1/20 0.31
KCNC1 P48547 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16836295 0.73 KDM4E (0.50) MAOAMAOB
SCHEMBL3537473 0.73 MAOA (0.42) MAOAMAOBNFKB1DYRK1AHTR2C
SCHEMBL8274132 0.72 KDM4E (0.53)
SCHEMBL31168619 0.64 AXL (0.37)
SCHEMBL31168396 0.64
SCHEMBL29962923 0.63 SMN1; SMN2 (0.33) DYRK1A
SCHEMBL29059719 0.63 SMN1; SMN2 (0.33) DYRK1A
SCHEMBL24655972 0.62 DYRK1A (0.33) DYRK1A
SCHEMBL457106 0.62 DYRK1A (0.38) DYRK1A
SCHEMBL4771419 0.62 DYRK1A (0.36) DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111675715-B Difuranopyridine derivative and preparation method thereof 江苏建筑职业技术学院 2022-10-18 CN claimed
CN-111675715-A Difuranopyridine derivative and preparation method thereof 江苏建筑职业技术学院 2020-09-18 CN claimed
US-20250127055-A1 LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, AND FUSED POLYCYCLIC COMPOUND FOR THE LIGHT-EMITTING ELEMENT SAMSUNG DISPLAY CO., LTD. (KR) 2025-04-17 US disclosed
CN-111675715-B Difuranopyridine derivative and preparation method thereof 江苏建筑职业技术学院 2022-10-18 CN disclosed
CN-111675715-B Difuranopyridine derivative and preparation method thereof 江苏建筑职业技术学院 2022-10-18 CN disclosed
CN-111675715-A Difuranopyridine derivative and preparation method thereof 江苏建筑职业技术学院 2020-09-18 CN disclosed
CN-111675715-A Difuranopyridine derivative and preparation method thereof 江苏建筑职业技术学院 2020-09-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127055-A1 LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, AND FUSED POLYCYCLIC COMPOUND FOR THE LIGHT-EMITTING ELEMENT NR2E3, CCNE2, NBAS MAOA 2884/4885MAOB 2147/4885NFKB1 1963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.