Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FABP6 | P51161 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17650910 | 0.82 | OPRM1 (0.55) | OPRM1OPRL1GRIN2BTMEM97MEN1 | |
| SCHEMBL17650912 | 0.82 | OPRM1 (0.55) | OPRM1OPRL1GRIN2BTMEM97MEN1 | |
| SCHEMBL20818793 | 0.79 | OPRM1 (0.57) | OPRM1OPRL1GRIN2BTMEM97MEN1 | |
| SCHEMBL20819030 | 0.79 | OPRM1 (0.57) | OPRM1OPRL1GRIN2BTMEM97MEN1 | |
| SCHEMBL20818791 | 0.79 | OPRM1 (0.57) | OPRM1OPRL1GRIN2BTMEM97MEN1 | |
| SCHEMBL28453033 | 0.79 | CCR5 (0.46) | GRIN2BMEN1KMT2ARAB9A | |
| SCHEMBL9044015 | 0.78 | OPRM1 (0.53) | OPRM1OPRL1GRIN2BTMEM97MEN1 | |
| SCHEMBL3644107 | 0.77 | OPRM1 (0.52) | OPRM1OPRL1GRIN2BTMEM97MEN1 | |
| SCHEMBL2588468 | 0.77 | OPRM1 (0.61) | OPRM1OPRL1GRIN2BTMEM97MEN1 | |
| SCHEMBL20576058 | 0.77 | OPRM1 (0.55) | OPRM1OPRL1GRIN2BTMEM97MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236431-B | Purinone Compounds and Their Use in the Treatment of Cancer | 阿斯利康(瑞典)有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-111566089-B | IRE1 small molecule inhibitors | 康奈尔大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-112236431-A | Purinone compounds and their use in the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2021-01-15 | — | — | CN | disclosed |
| CN-111566089-A | IRE1 small molecule inhibitor | 康奈尔大学 | 2020-08-21 | — | — | CN | disclosed |