Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29022929 | 0.77 | KMT2A (0.49) | TSHRGAAKMT2AMEN1 | |
| Benzoic Acid SCHEMBL28616712 | 0.71 | HRH3 (0.44) | ACHEDAOTSHRNAPRTUSP2 | |
| Benzoic Acid SCHEMBL2806428 | 0.69 | TSHR (0.64) | ACHEDAOTSHRNAPRTUSP2 | |
| Benzoic Acid SCHEMBL8427607 | 0.67 | DAO (0.54) | ACHEDAOTSHRNAPRTUSP2 | |
| Benzoic Acid SCHEMBL27819561 | 0.67 | TSHR (0.58) | ACHEDAOTSHRNAPRTUSP2 | |
| Benzoic Acid SCHEMBL4089426 | 0.67 | TSHR (0.58) | ACHEDAOTSHRNAPRTUSP2 | |
| Benzoic Acid SCHEMBL5142456 | 0.66 | TSHR (0.93) | DAOTSHRNAPRTTP53CES2 | |
| Benzoic Acid SCHEMBL29039829 | 0.66 | TSHR (0.64) | DAOTSHRNAPRTNPC1TP53 | |
| Benzoic Acid SCHEMBL16631990 | 0.65 | TSHR (0.70) | DAOTSHRNAPRTTP53GAA | |
| Benzoic Acid SCHEMBL4098363 | 0.65 | TSHR (0.56) | ACHEDAOTSHRNAPRTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724071-A | Preparation method and equipment of hindered amine light stabilizer | 浙江合糖科技有限公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-211339353-U | Preparation equipment of hindered amine light stabilizer | 浙江合糖科技有限公司 | 2020-08-25 | — | — | CN | disclosed |