Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201492 | 0.78 | MKNK1 (0.52) | IRAK4CYP11B2LRRK2MKNK1MKNK2 | |
| SCHEMBL25269630 | 0.78 | CYP11B2 (0.47) | CHEK1AURKADAPK3CSNK1A1GSK3A | |
| SCHEMBL29695764 | 0.78 | CHEK1 (0.41) | IRAK4CHEK1AURKADAPK3CSNK1A1 | |
| SCHEMBL30204846 | 0.78 | PIM3 (0.41) | PIM3 | |
| SCHEMBL1701230 | 0.77 | CHEK1 (0.46) | IRAK4CHEK1AURKADAPK3CSNK1A1 | |
| SCHEMBL11998910 | 0.73 | LRRK2 (0.43) | IRAK4MAPTLRRK2MKNK1MKNK2 | |
| SCHEMBL13836976 | 0.73 | CHEK1 (0.50) | CHEK1AURKADAPK3CSNK1A1GSK3A | |
| SCHEMBL6087069 | 0.71 | HSP90AA1 (0.41) | MAPTLRRK2CDC7HSP90AA1 | |
| SCHEMBL21295429 | 0.70 | NR3C1 (0.54) | IRAK4CHEK1AURKADAPK3CSNK1A1 | |
| SCHEMBL30127430 | 0.70 | NR3C1 (0.54) | IRAK4CHEK1AURKADAPK3CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111587112-A | Rho-related inhibitors of coiled coil protein kinase | 卡德门企业有限公司 | 2020-08-25 | — | — | CN | disclosed |