Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1544736 | 0.86 | TSHR (0.71) | FFAR1RAB9ANPC1L3MBTL1KMT2A | |
| SCHEMBL4611029 | 0.84 | ALDH1A1 (0.68) | FFAR1RAB9ANPC1L3MBTL1KMT2A | |
| SCHEMBL4658742 | 0.82 | KCNH2 (0.64) | FFAR1RAB9ANPC1L3MBTL1KMT2A | |
| SCHEMBL1544555 | 0.82 | KMT2A (0.56) | FFAR1RAB9ANPC1L3MBTL1KMT2A | |
| SCHEMBL5759070 | 0.81 | TSHR (0.64) | FFAR1RAB9ANPC1L3MBTL1KMT2A | |
| SCHEMBL1544535 | 0.81 | RAB9A (0.55) | FFAR1RAB9ANPC1L3MBTL1KMT2A | |
| SCHEMBL30566758 | 0.81 | RAB9A (0.55) | FFAR1RAB9ANPC1L3MBTL1KMT2A | |
| SCHEMBL1544588 | 0.80 | RAB9A (0.57) | FFAR1RAB9ANPC1L3MBTL1KMT2A | |
| SCHEMBL11555365 | 0.80 | AKR1B1 (0.51) | FFAR1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL8293860 | 0.80 | NOTUM (0.67) | FFAR1RAB9ANPC1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111630032-B | Novel methionine metabolic pathway inhibitor | 米加尔-加利里研究院有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-111699182-A | Novel methionine metabolic pathway inhibitors | 米加尔-加利里研究院有限公司 | 2020-09-22 | — | — | CN | disclosed |
| CN-111630032-A | Novel methionine metabolic pathway inhibitors | 米加尔-加利里研究院有限公司 | 2020-09-04 | — | — | CN | disclosed |