Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31395397 | 0.87 | ADRA2A (0.47) | ADRA2ALMNAMAPTHTTBLM | |
| SCHEMBL27198030 | 0.83 | CYP19A1 (0.37) | ADRA2ALMNAMAPTHTTBLM | |
| SCHEMBL27198141 | 0.83 | CYP19A1 (0.37) | ADRA2ALMNAMAPTHTTBLM | |
| Hydrochloric Acid SCHEMBL31136488 | 0.82 | CYP19A1 (0.36) | ADRA2ALMNAMAPTHTTBLM | |
| SCHEMBL29134322 | 0.81 | ADRA2A (0.42) | ADRA2ALMNAMAPTHTTBLM | |
| SCHEMBL14518509 | 0.81 | KDM4E (0.41) | MAPTPDPK1MAP3K14 | |
| SCHEMBL29920817 | 0.81 | ADRA2A (0.47) | ADRA2AKDM4CPDPK1MAP3K14 | |
| SCHEMBL16794282 | 0.79 | KDM4C (0.47) | ADRA2AKDM4C | |
| SCHEMBL23976524 | 0.79 | KDM4C (0.42) | ADRA2AKDM4CHTR2A | |
| SCHEMBL19889279 | 0.78 | ADRA2A (0.50) | ADRA2ALMNAMAPTHTTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909083-B | Inhibitors of histone demethylase | 赛尔基因昆蒂赛尔研究公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-111909083-A | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-106660982-B | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2020-09-08 | — | — | CN | disclosed |