Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.78 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959512 | 0.90 | MEN1 (0.73) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28453421 | 0.89 | LMNA (0.77) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8242227 | 0.88 | NPC1 (0.70) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4955792 | 0.85 | MEN1 (0.69) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21323255 | 0.85 | NPC1 (0.76) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16346179 | 0.85 | NPC1 (0.67) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3426467 | 0.84 | MAPT (0.69) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4957089 | 0.84 | LMNA (1.00) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4957083 | 0.84 | LMNA (0.77) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16597184 | 0.83 | ALDH1A1 (0.65) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111471023-A | Method for synthesizing quinazolinone compound under photocatalysis condition | 河南大学 | 2020-07-31 | — | — | CN | disclosed |