Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24397844 | 0.94 | CHIA (0.39) | CHIADHODHPDE4BNTRK1KDM4E | |
| SCHEMBL28897977 | 0.94 | DHODH (0.35) | DHODHKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL24397868 | 0.87 | DHODH (0.38) | DHODHNTRK1KDM4EMEN1ALDH1A1 | |
| SCHEMBL28451756 | 0.87 | CHIA (0.36) | CHIADHODHPDE4BNTRK1 | |
| SCHEMBL24397793 | 0.86 | CHIA (0.39) | CHIADHODHPDE4BNTRK1ALDH1A1 | |
| SCHEMBL28455280 | 0.85 | DHODH (0.37) | DHODHKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL29181526 | 0.84 | DHODH (0.36) | DHODHKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL29181576 | 0.84 | DHODH (0.36) | DHODHKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL29181608 | 0.84 | DHODH (0.36) | DHODHKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL28451074 | 0.84 | DHODH (0.36) | DHODHKDM4EMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111662269-B | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-111662269-A | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | disclosed |