Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24397793 | 0.95 | CHIA (0.39) | CHIADHODHPDE4BNTRK1 | |
| SCHEMBL28451730 | 0.92 | DHODH (0.37) | DHODHNTRK1 | |
| SCHEMBL28447607 | 0.90 | CHIA (0.39) | CHIADHODHPDE4BNTRK1 | |
| SCHEMBL28458430 | 0.90 | DHODH (0.40) | CHIADHODHPDE4BNTRK1 | |
| SCHEMBL28455067 | 0.89 | POLB (0.39) | DHODHPDE4B | |
| SCHEMBL24397959 | 0.88 | DHODH (0.39) | DHODHNTRK1 | |
| SCHEMBL28451011 | 0.87 | HPGD (0.39) | DHODH | |
| SCHEMBL24397844 | 0.87 | CHIA (0.39) | CHIADHODHPDE4BNTRK1 | |
| SCHEMBL28451061 | 0.87 | CHIA (0.35) | CHIADHODHPDE4BNTRK1 | |
| SCHEMBL29912749 | 0.84 | DHODH (0.41) | CHIADHODHPDE4BNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111662269-B | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-111662269-A | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | disclosed |