Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | RORB | Q92753 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DHPS | P49366 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321052 | 0.80 | SQOR (0.41) | FYNNPC1MAPTCD274 | |
| SCHEMBL3841461 | 0.78 | PDE4D (0.52) | FYNRORCRORBPDE4DPDE4B | |
| SCHEMBL5099550 | 0.77 | PDE4D (0.56) | FYNRORCRORBPDE4DPDE4B | |
| SCHEMBL3787052 | 0.76 | PDE4B (0.52) | FYNRORCRORBPDE4DPDE4B | |
| SCHEMBL3797410 | 0.74 | HTR7 (0.55) | RORCRORBPDE4DPDE4BDHPS | |
| SCHEMBL26063261 | 0.73 | FYN (0.51) | FYNMAPTCYP1A1CYP1A2CYP2E1 | |
| SCHEMBL30076250 | 0.73 | KDM1A (0.48) | MAPTCYP1A1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL27649562 | 0.73 | TSHR (0.45) | FYNRORCRORBPDE4DPDE4B | |
| SCHEMBL16290445 | 0.73 | MAPK10 (0.45) | FYNRORCRORBPDE4DPDE4B | |
| SCHEMBL29634014 | 0.72 | PDE4B (0.51) | FYNRORCRORBPDE4DPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531705-B | Bicyclic ketone sulfonamide compounds | 美国安进公司 | 2020-09-18 | — | — | CN | disclosed |