Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Enoxacin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.98 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.98 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.98 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.98 |
| ▸ | EDNRA | P25101 | 1/20 | 0.98 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.98 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | BRD4 | O60885 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Enoxacin SCHEMBL29896709 | 1.00 | LMNA (0.98) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL11289413 | 1.00 | LMNA (0.98) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL2635855 | 0.99 | LMNA (1.00) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL29384458 | 0.99 | LMNA (1.00) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL33963 | 0.99 | LMNA (1.00) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL28065171 | 0.98 | LMNA (0.98) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL11023659 | 0.98 | LMNA (0.98) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL29108687 | 0.98 | LMNA (0.98) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL11283102 | 0.94 | LMNA (0.91) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL27515554 | 0.93 | LMNA (0.89) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119970737-A | Application of enoxacin sesquihydrate and related products | 三明市中西医结合医院 | 2025-05-13 | — | — | CN | disclosed |
| CN-113313159-B | High-throughput cluster analysis method for veterinary drugs | 广西壮族自治区水产科学研究院 | 2022-09-30 | — | — | CN | disclosed |
| CN-107727769-B | Method for rapidly screening and confirming veterinary drug residues in milk | 蒋万枫 | 2020-11-27 | — | — | CN | disclosed |
| CN-111999491-A | Ofloxacin detection kit and detection method thereof | 深圳容金科技有限公司 | 2020-11-27 | — | — | CN | disclosed |
| CN-111548965-A | Donkey-derived bacillus pumilus and application thereof in preparation of medicine for treating diarrhea of donkey colt | 山东省农业科学院生物技术研究中心 | 2020-08-18 | — | — | CN | disclosed |