Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30477988 | 1.00 | ALDH1A1 (0.36) | ALDH1A1MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL30477995 | 0.88 | HTR2A (0.34) | SMN1; SMN2NPC1MAPK1RAB9APOLB | |
| SCHEMBL28447636 | 0.88 | HTR2A (0.34) | SMN1; SMN2NPC1MAPK1RAB9APOLB | |
| SCHEMBL28451556 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2RAB9A | |
| SCHEMBL30477977 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2RAB9A | |
| SCHEMBL30477985 | 0.81 | PARP1 (0.35) | CYP1A2HTR2B | |
| SCHEMBL28897519 | 0.81 | HSP90AA1 (0.39) | MAPTSMN1; SMN2NPC1RAB9AHTR2B | |
| SCHEMBL30477987 | 0.81 | HSP90AA1 (0.39) | MAPTSMN1; SMN2NPC1RAB9AHTR2B | |
| SCHEMBL28453681 | 0.81 | METAP1 (0.39) | ALDH1A1MAPTLMNAL3MBTL1TDP1 | |
| SCHEMBL30477983 | 0.81 | METAP1 (0.39) | ALDH1A1MAPTLMNAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533764-B | Method for preparing siloxyindene derivative by utilizing domino reaction | 杭州师范大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-111533764-A | Method for preparing siloxyindene derivative by using domino reaction | 杭州师范大学 | 2020-08-14 | — | — | CN | disclosed |