Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28447636 | 1.00 | HTR2A (0.34) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL30477988 | 0.88 | ALDH1A1 (0.36) | HTR2AHTR2CNPC1POLBMAPK1 | |
| SCHEMBL28451631 | 0.88 | ALDH1A1 (0.36) | HTR2AHTR2CNPC1POLBMAPK1 | |
| SCHEMBL28451556 | 0.79 | ALDH1A1 (0.41) | POLBRAB9ASMN1; SMN2 | |
| SCHEMBL30477977 | 0.79 | ALDH1A1 (0.41) | POLBRAB9ASMN1; SMN2 | |
| SCHEMBL28447085 | 0.78 | PARP1 (0.35) | — | |
| SCHEMBL28453681 | 0.78 | METAP1 (0.39) | — | |
| SCHEMBL30477987 | 0.78 | HSP90AA1 (0.39) | PTAFRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30477983 | 0.78 | METAP1 (0.39) | — | |
| SCHEMBL28897519 | 0.78 | HSP90AA1 (0.39) | PTAFRNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533764-B | Method for preparing siloxyindene derivative by utilizing domino reaction | 杭州师范大学 | 2023-06-06 | — | — | CN | disclosed |