SCHEMBL2845185

SCHEMBL2845185

CCN(CC)c1ccc(C)c(C=O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 16/20 0.58
L3MBTL1 Q9Y468 4/20 0.58
ALDH1A3 P47895 2/20 0.55
ALDH3A1 P30838 1/20 0.55
MAPT P10636 10/20 0.53
KDM4E B2RXH2 5/20 0.51
HPGD P15428 3/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
NPSR1 Q6W5P4 1/20 0.51
S100B P04271 1/20 0.50
RAB9A P51151 3/20 0.49
MAPK1 P28482 2/20 0.47
HSD17B10 Q99714 2/20 0.47
GLA P06280 2/20 0.47
IGLV6-57 P01721 1/20 0.47
CYP3A4 P08684 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
ATM Q13315 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9513869 0.87 ALDH1A1 (0.47) ALDH1A1L3MBTL1ALDH1A3ALDH3A1MAPT
SCHEMBL2845181 0.85 ALDH1A1 (0.63) ALDH1A1L3MBTL1ALDH1A3ALDH3A1MAPT
SCHEMBL28379902 0.85 ALDH1A1 (0.67) ALDH1A1L3MBTL1ALDH1A3ALDH3A1MAPT
SCHEMBL7678827 0.83 ALDH1A1 (0.65) ALDH1A1L3MBTL1ALDH1A3ALDH3A1MAPT
SCHEMBL5462848 0.80 ALDH1A1 (0.57) ALDH1A1L3MBTL1ALDH1A3ALDH3A1MAPT
SCHEMBL31268246 0.80 ALDH1A1 (0.57) ALDH1A1L3MBTL1ALDH1A3ALDH3A1MAPT
SCHEMBL8964348 0.79 CYP2A6 (0.48) ALDH1A1L3MBTL1MAPTKDM4EMAPK1
SCHEMBL10787489 0.78 CYP2C19 (0.53) ALDH1A1LMNACRHBPCRHR2TSHR
SCHEMBL10788127 0.78 QPCT (0.49) ALDH1A1L3MBTL1HPGDSMN1; SMN2LMNA
SCHEMBL15800618 0.78 ALDH1A1 (0.63) ALDH1A1L3MBTL1ALDH1A3ALDH3A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100047508-A1 OPTICAL STORAGE DEVICE HAVING LIMITED-USE CONTENT AND METHOD FOR MAKING SAME GENERAL ELECTRIC COMPANY (US) 2010-02-25 US disclosed
US-20090263612-A1 System and Method for Photobleaching of Optical Media NBC UNIVERSAL, INC. (US) 2009-10-22 US disclosed
US-20090246441-A1 System and Method for Photobleaching of Optical Media NBC UNIVERSAL, INC. (US) 2009-10-01 US disclosed
WO-2007064526-A2 OPTICAL STORAGE DEVICE HAVING LIMITED-USE CONTENT AND METHOD FOR MAKING SAME GENERAL ELECTRIC COMPANY (US) 2007-06-07 WO disclosed
US-20070122735-A1 Optical storage device having limited-use content and method for making same GENERAL ELECTRIC COMPANY 2007-05-31 US disclosed
US-6350305-B1 PHASE CHANGE INKS XEROX CORPORATION 2002-02-26 US disclosed
US-4078934-A Photosensitive, image-forming composition containing a leuco 2,3-disubstituted-1-indanone and a photooxidant E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-03-14 US disclosed
US-3992450-A PHOTOSENSITIVE COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-11-16 US disclosed