Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27935867 | 0.78 | ALDH1A1 (0.68) | ALDH1A1TSHRALOX15L3MBTL1NPSR1 | |
| SCHEMBL28455262 | 0.77 | ALDH1A1 (0.62) | ALDH1A1TSHRALOX15L3MBTL1NPSR1 | |
| SCHEMBL28188974 | 0.75 | ALDH1A1 (0.41) | ALDH1A1TSHRALOX15ESRRAFAAH | |
| SCHEMBL28451467 | 0.74 | KCNN4 (0.46) | ALDH1A1TSHRMGLLSMN1; SMN2KCNN4 | |
| SCHEMBL28456095 | 0.74 | KCNN4 (0.44) | ALDH1A1TSHRMGLLTDP1KCNN4 | |
| SCHEMBL28898079 | 0.74 | ALDH1A1 (0.51) | ALDH1A1TSHRNPSR1SMN1; SMN2KCNN4 | |
| SCHEMBL28449970 | 0.74 | KCNN4 (0.60) | KCNN4 | |
| SCHEMBL30006797 | 0.72 | KCNN4 (0.38) | ALDH1A1TSHRL3MBTL1NPSR1SMN1; SMN2 | |
| SCHEMBL12530575 | 0.71 | FAAH (0.42) | ALDH1A1TSHRALOX15ESRRAFAAH | |
| SCHEMBL30353932 | 0.71 | ALDH1A1 (0.49) | ALDH1A1TSHRALOX15SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501198-B | Sulfoxide tetrazole derivative and preparation method and application thereof | 南京农业大学 | 2020-08-18 | — | — | CN | disclosed |