Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.33 |
| ▸ | GRM5 | P41594 | 6/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779792 | 0.88 | GRM5 (0.42) | GRM5NPC1RAB9AMAPK1 | |
| SCHEMBL25390011 | 0.80 | GRM5 (0.34) | DPP4DPP8DPP7DPP9GRM5 | |
| SCHEMBL28449516 | 0.78 | DRD2 (0.43) | DPP4DPP8DPP7DPP9GRM5 | |
| SCHEMBL5642534 | 0.75 | DPP4 (0.50) | DPP4DPP8DPP7DPP9GRM5 | |
| SCHEMBL26094092 | 0.69 | ADORA1 (0.40) | — | |
| SCHEMBL3441635 | 0.68 | HDAC6 (0.43) | — | |
| SCHEMBL15332856 | 0.68 | PDK1 (0.48) | GRM5NPC1RAB9A | |
| SCHEMBL15896560 | 0.68 | PDK1 (0.48) | GRM5NPC1RAB9A | |
| SCHEMBL17377204 | 0.68 | CSNK2A2 (0.41) | NPC1RAB9AMAPK1 | |
| SCHEMBL21040978 | 0.67 | ADORA1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922430-B | 2-substituted benzimidazole-4-formamide compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2020-09-04 | — | — | CN | disclosed |