Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 9/20 | 0.67 |
| ▸ | NPC1 | O15118 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | NT5E | P21589 | 1/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.58 |
| ▸ | SCD | O00767 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3803935 | 0.85 | RAB9A (0.79) | TP53RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL774978 | 0.83 | LCK (0.78) | TP53CHRM4CHRM5ADORA3HTR2A | |
| SCHEMBL3589179 | 0.82 | SCD (0.66) | TP53RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL28458980 | 0.81 | ALOX5 (0.66) | TP53RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL28482095 | 0.80 | RAB9A (0.84) | TP53RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL259827 | 0.79 | TP53 (0.62) | TP53RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL8738341 | 0.79 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL15626326 | 0.79 | KMT2A (0.61) | TP53RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL8881384 | 0.79 | RAB9A (0.77) | TP53RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL23440063 | 0.78 | SCD (0.60) | TP53RAB9ANPC1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864073-B | N-thiazolyl pyridine carboxamide derivative and preparation method and application thereof | 湖南大学 | 2020-08-18 | — | — | CN | disclosed |