SCHEMBL28453301

SCHEMBL28453301

CCCC[SiH2]Oc1ccccc1OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA12 O43570 1/20 0.48
CA4 P22748 1/20 0.48
CA14 Q9ULX7 1/20 0.48
ALOX5 P09917 1/20 0.40
PTGS2 P35354 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
DRD2 P14416 1/20 0.40
DRD3 P35462 1/20 0.40
ALDH1A1 P00352 3/20 0.39
HTT P42858 2/20 0.39
MAPK1 P28482 1/20 0.39
TP53 P04637 2/20 0.39
HTR1A P08908 1/20 0.39
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28297271 0.95 CA12 (0.46) CA1CA2CA7CA9CA12
SCHEMBL28459964 0.89 CA1 (0.52) CA1CA2CA7CA9CA12
SCHEMBL3295650 0.81 CYP2C19 (0.38) PTGS2TDP1DRD2ALDH1A1CYP1A2
SCHEMBL28200033 0.80 CA1 (0.56) CA1CA2CA7CA9CA12
SCHEMBL25395319 0.78 SMN1; SMN2 (0.43) ALOX5PTGS2HTR1ASMN1; SMN2
1,2-Dimethoxybenzene SCHEMBL15206586 0.78 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL17542560 0.77 CYP1A2 (0.35) ALOX5PTGS2L3MBTL1CYP1A2CYP2C19
SCHEMBL705034 0.75 LTA4H (0.47) CA4DRD2DRD3ALDH1A1HTT
1-Methoxy-2-Butoxybenzene SCHEMBL364856 0.72 L3MBTL1 (0.63) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL22800426 0.72 CA1 (0.56) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108250754-B Silicon-containing resin composition, silicon-containing resin film, silica film, light-emitting display element panel, and light-emitting display device 东京应化工业株式会社 2022-01-25 CN disclosed
CN-107922733-B Polyimide precursor composition 东京应化工业株式会社 2020-09-11 CN disclosed