Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | LAP3 | P28838 | 2/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5138360 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53DNM1LMNA | |
| Bromide SCHEMBL924077 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53DNM1LMNA | |
| Bromide SCHEMBL5088250 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53DNM1LMNA | |
| Bromide SCHEMBL139792 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53DNM1LMNA | |
| Bromide SCHEMBL923748 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53DNM1LMNA | |
| Bromide SCHEMBL489783 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53DNM1LMNA | |
| Bromide SCHEMBL923753 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53DNM1LMNA | |
| Bromide SCHEMBL3092841 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53DNM1LMNA | |
| Bromide SCHEMBL475827 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53DNM1LMNA | |
| Bromide SCHEMBL3217101 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53DNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107840344-B | Titanium-silicon molecular sieve and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-08-18 | — | — | CN | disclosed |
| CN-107840347-B | Titanium-silicon molecular sieve and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-08-18 | — | — | CN | disclosed |