Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | FABP7 | O15540 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL389123 | 0.87 | TSHR (0.61) | KMT2AMEN1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL28104834 | 0.85 | TSHR (0.59) | KMT2AMEN1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL28449328 | 0.82 | KMT2A (0.49) | KMT2AMEN1RXFP1TSHRMAPT | |
| SCHEMBL28897993 | 0.82 | APP (0.50) | KMT2AMEN1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL28519236 | 0.82 | MEN1 (0.49) | KMT2AMEN1LMNATSHRL3MBTL1 | |
| SCHEMBL28454755 | 0.82 | MEN1 (0.53) | KMT2AMEN1LMNATSHRMAPT | |
| SCHEMBL28445150 | 0.79 | NPC1 (0.50) | KMT2AMEN1TSHRMAPTL3MBTL1 | |
| SCHEMBL27956679 | 0.78 | TSHR (0.47) | KMT2AMEN1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL28519668 | 0.77 | TSHR (0.50) | KMT2AMEN1TSHRALDH1A1KDM4E | |
| SCHEMBL27956676 | 0.77 | MEN1 (0.51) | KMT2AMEN1LMNATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031639-A | Preparation method of biphosphonate with P-O-C-P structure | 烟台大学 | 2022-02-11 | — | — | CN | disclosed |
| CN-107602609-B | Method for preparing organic phosphate compound by using P (O) -OH compound and methyl-containing substituted aromatic hydrocarbon | 湖南理工学院 | 2020-07-21 | — | — | CN | disclosed |