Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28454755 | 0.95 | MEN1 (0.53) | MEN1KMT2APOLBTSHRHPGD | |
| SCHEMBL389123 | 0.89 | TSHR (0.61) | MEN1KMT2ATSHRCETPALDH1A1 | |
| SCHEMBL28104834 | 0.87 | TSHR (0.59) | MEN1KMT2ATSHRCETPALDH1A1 | |
| SCHEMBL28442764 | 0.83 | IDO1 (0.50) | MEN1KMT2APOLBTSHRHPGD | |
| SCHEMBL28520294 | 0.83 | RAB9A (0.52) | MEN1KMT2ATSHRNPC1RAB9A | |
| SCHEMBL28519668 | 0.83 | TSHR (0.50) | MEN1KMT2APOLBTSHRHPGD | |
| SCHEMBL28445150 | 0.78 | NPC1 (0.50) | MEN1KMT2APOLBTSHRNPC1 | |
| SCHEMBL28510606 | 0.78 | AKR1C3 (0.56) | MEN1KMT2ATSHRHPGDNPC1 | |
| SCHEMBL28519236 | 0.77 | MEN1 (0.49) | MEN1KMT2ATSHRHPGDLMNA | |
| SCHEMBL28453734 | 0.77 | KMT2A (0.49) | MEN1KMT2APOLBTSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980306-B | Preparation method for hypophosphorous acid / phosphorous acid/ phosphate compounds by adopting P(O)-OH-contained compounds | 湖南大学 | 2017-02-15 | — | — | CN | disclosed |
| CN-103980306-A | Preparation method for hypophosphorous acid / phosphorous acid/ phosphate compounds by adopting P(O)-OH-contained compounds | UNIV HUNAN | 2014-08-13 | — | — | CN | disclosed |