Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28519236 | 0.95 | MEN1 (0.49) | TSHRMEN1KMT2AGAAAR | |
| SCHEMBL389123 | 0.89 | TSHR (0.61) | TSHRMEN1KMT2ACETPPDPK1 | |
| SCHEMBL28104834 | 0.87 | TSHR (0.59) | TSHRMEN1KMT2ACETPPDPK1 | |
| SCHEMBL27956676 | 0.83 | MEN1 (0.51) | TSHRMEN1KMT2ACETPPOLB | |
| SCHEMBL27956685 | 0.80 | TSHR (0.47) | TSHRMEN1KMT2ACETPPDPK1 | |
| SCHEMBL28520294 | 0.80 | RAB9A (0.52) | TSHRMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL28510606 | 0.78 | AKR1C3 (0.56) | TSHRMEN1KMT2AGAAHPGD | |
| SCHEMBL28897993 | 0.77 | APP (0.50) | TSHRMEN1KMT2ACETPALDH1A1 | |
| SCHEMBL28453734 | 0.77 | KMT2A (0.49) | TSHRMEN1KMT2AGAAPOLB | |
| SCHEMBL28454755 | 0.77 | MEN1 (0.53) | TSHRMEN1KMT2ACETPPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749396-B | Method for preparing organic phosphonate compound by efficiently esterifying compound containing P (O) -OH and alcohol | 湖南理工学院 | 2020-12-15 | — | — | CN | disclosed |