SCHEMBL28454152

SCHEMBL28454152

COc1ccc(Oc2ccc(N3C(=O)C=CC3=O)cc2)cc1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 13/20 0.89
FAAH O00519 4/20 0.58
POLB P06746 1/20 0.56
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
HSP90AA1 P07900 2/20 0.53
PKM P14618 2/20 0.53
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
HPGD P15428 1/20 0.53
HTT P42858 1/20 0.53
CCR6 P51684 1/20 0.53
ATM Q13315 1/20 0.53
G6PD P11413 1/20 0.50
TLR9 Q9NR96 1/20 0.50
ELANE P08246 1/20 0.50
GSK3A P49840 1/20 0.49
GSK3B P49841 1/20 0.49
MAPK1 P28482 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL136617 0.94 MGLL (1.00) MGLLFAAHPOLBMEN1KMT2A
SCHEMBL28071934 0.92 MGLL (0.96) MGLLFAAHPOLBMEN1KMT2A
SCHEMBL487033 0.90 MGLL (0.84) MGLLFAAHMEN1KMT2AHSP90AA1
SCHEMBL331752 0.90 MGLL (0.84) MGLLFAAHMEN1KMT2AHSP90AA1
SCHEMBL4385482 0.90 MGLL (0.84) MGLLFAAHMEN1KMT2AHSP90AA1
SCHEMBL24541383 0.89 MGLL (0.70) MGLLFAAHPOLBMEN1KMT2A
SCHEMBL27122580 0.89 MGLL (0.70) MGLLFAAHPOLBMEN1KMT2A
SCHEMBL5068628 0.85 MGLL (0.77) MGLLFAAHMEN1KMT2AHSP90AA1
SCHEMBL9245833 0.84 MGLL (0.75) MGLLFAAHMEN1KMT2AHSP90AA1
SCHEMBL10953934 0.84 MGLL (0.79) MGLLFAAHPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109971175-B Modified maleimide resin composition, prepreg and laminated board prepared from same 苏州生益科技有限公司 2021-09-21 CN disclosed
CN-109054381-B Modified maleimide resin composition, prepreg and laminated board prepared from same 苏州生益科技有限公司 2020-09-11 CN disclosed