Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB2 | Q9UBS0 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2373414 | 0.78 | MEN1 (0.42) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL2218274 | 0.75 | RPS6KB2 (0.50) | RPS6KB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL820251 | 0.75 | RPS6KB2 (0.50) | RPS6KB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL16291133 | 0.74 | L3MBTL1 (0.57) | RPS6KB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3545 | 0.74 | L3MBTL1 (0.57) | RPS6KB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2877926 | 0.73 | ADORA2A (0.42) | RPS6KB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2049905 | 0.73 | RPS6KB2 (0.41) | RPS6KB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3473292 | 0.73 | RPS6KB2 (0.41) | RPS6KB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11624487 | 0.73 | RPS6KB2 (0.44) | RPS6KB2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL623377 | 0.72 | MAPT (0.41) | RPS6KB2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438376-B | 4, 5-diheteroaryl substituted triazole compound and preparation method and application thereof | 扬州工业职业技术学院 | 2020-09-04 | — | — | CN | disclosed |