Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RPS6KB2 | Q9UBS0 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28454459 | 0.72 | RPS6KB2 (0.50) | MAPTRPS6KB2ADORA2AADORA1KDM4E | |
| SCHEMBL11624487 | 0.69 | RPS6KB2 (0.44) | MAPTRPS6KB2ADORA2AADORA1KDM4E | |
| SCHEMBL624711 | 0.68 | MEN1 (0.45) | MAPTRPS6KB2ADORA2AKDM4EALDH1A1 | |
| SCHEMBL1907213 | 0.68 | MAPT (0.41) | MAPTRPS6KB2ADORA2AADORA1KDM4E | |
| SCHEMBL28251777 | 0.67 | MAPT (0.57) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL11485920 | 0.66 | MAPT (0.42) | MAPTRPS6KB2KDM4EALDH1A1HPGD | |
| SCHEMBL1701249 | 0.65 | KDM4E (0.41) | MAPTRPS6KB2ADORA2AKDM4EALDH1A1 | |
| SCHEMBL5210609 | 0.65 | SMN1; SMN2 (0.49) | MAPTADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL26672756 | 0.65 | GPR119 (0.59) | MAPTRPS6KB2ADORA2AKDM4EALDH1A1 | |
| SCHEMBL14334168 | 0.64 | SMPD3 (0.60) | MAPTADORA2AADORA1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |