Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 5/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354362 | 0.93 | MAPK1 (0.54) | MAPK1KMT2AALDH1A1TSHRMGLL | |
| SCHEMBL79589 | 0.93 | MAPK1 (0.54) | MAPK1KMT2AALDH1A1TSHRMGLL | |
| SCHEMBL28454818 | 0.87 | NSD2 (0.45) | MAPK1KMT2AALDH1A1TSHRMGLL | |
| SCHEMBL28626188 | 0.84 | MAPK1 (0.46) | MAPK1KMT2AALDH1A1TSHRMGLL | |
| SCHEMBL28297910 | 0.82 | MGLL (0.55) | MAPK1KMT2AALDH1A1MGLLFAAH | |
| SCHEMBL15991691 | 0.81 | MAPK1 (0.46) | MAPK1KMT2AALDH1A1MGLLFAAH | |
| SCHEMBL29072379 | 0.80 | MGLL (0.46) | MAPK1KMT2AALDH1A1TSHRMGLL | |
| SCHEMBL10328160 | 0.79 | NSD2 (0.49) | MAPK1KMT2AALDH1A1TSHRMGLL | |
| SCHEMBL10328161 | 0.79 | NSD2 (0.53) | MAPK1KMT2AALDH1A1MGLLFAAH | |
| SCHEMBL15337086 | 0.79 | MGLL (0.47) | MAPK1KMT2AALDH1A1MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111721931-A | Solid-phase time-resolved fluorescence immune marker and preparation method and application thereof | 广州万孚生物技术股份有限公司 | 2020-09-29 | — | — | CN | claimed |