Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | G6PD | P11413 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 5/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10328160 | 0.97 | NSD2 (0.49) | NSD2G6PDKEAP1NFE2L2MGLL | |
| SCHEMBL44173 | 0.88 | MAPK1 (0.41) | NSD2G6PDKEAP1NFE2L2HTT | |
| SCHEMBL79589 | 0.85 | MAPK1 (0.54) | MGLLHSP90AA1HTTFAAHALDH1A1 | |
| SCHEMBL29354362 | 0.85 | MAPK1 (0.54) | MGLLHSP90AA1HTTFAAHALDH1A1 | |
| SCHEMBL4528176 | 0.84 | HSP90AA1 (0.55) | MGLLHSP90AA1HTTNPSR1FAAH | |
| SCHEMBL13404895 | 0.81 | MGLL (0.37) | MGLLHTTTDP1ALDH1A1HPGD | |
| Succinic Acid SCHEMBL28454817 | 0.79 | MAPK1 (0.51) | NSD2G6PDKEAP1NFE2L2MGLL | |
| SCHEMBL17301093 | 0.78 | KMT2A (0.38) | G6PDHSP90AA1HTTNPSR1TDP1 | |
| SCHEMBL2575973 | 0.75 | CA12 (0.42) | MGLLTDP1MAPK1KMT2ACA12 | |
| SCHEMBL13404894 | 0.75 | CA12 (0.42) | NSD2G6PDKEAP1NFE2L2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120309021-A1 | DETECTION OF ANTIBODY THAT BINDS TO WATER SOLUBLE POLYMER-MODIFIED POLYPEPTIDES | BAXTER INTERNATIONAL INC. (US) | 2012-12-06 | — | — | US | disclosed |
| US-20120309021-A1 | DETECTION OF ANTIBODY THAT BINDS TO WATER SOLUBLE POLYMER-MODIFIED POLYPEPTIDES | BAXTER INTERNATIONAL INC. (US) | 2012-12-06 | — | — | US | disclosed |
| US-8216793-B2 | Detection of antibody that binds to water soluble polymer-modified polypeptides | BAXTER INTERNATIONAL INC. (US) | 2012-07-10 | — | — | US | disclosed |
| US-8216793-B2 | Detection of antibody that binds to water soluble polymer-modified polypeptides | BAXTER INTERNATIONAL INC. (US) | 2012-07-10 | — | — | US | disclosed |
| US-20110070592-A1 | DETECTION OF ANTIBODY THAT BINDS TO WATER SOLUBLE POLYMER-MODIFIED POLYPEPTIDES | BAXTER INTERNATIONAL INC. (US) | 2011-03-24 | — | — | US | disclosed |
| US-20110070592-A1 | DETECTION OF ANTIBODY THAT BINDS TO WATER SOLUBLE POLYMER-MODIFIED POLYPEPTIDES | BAXTER INTERNATIONAL INC. (US) | 2011-03-24 | — | — | US | disclosed |
| WO-2010138474-A1 | DETECTION OF ANTIBODY THAT BINDS TO WATER SOLUBLE POLYMER-MODIFIED POLYPEPTIDES | BAXTER INTERNATIONAL INC. (US) | 2010-12-02 | — | — | WO | disclosed |