Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 6/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24397959 | 0.94 | DHODH (0.39) | DHODHMALT1EPHX2TRPV1NTRK1 | |
| SCHEMBL28459476 | 0.93 | DHODH (0.38) | DHODHMALT1EPHX2TRPV1NTRK1 | |
| SCHEMBL28458430 | 0.91 | DHODH (0.40) | DHODHMALT1PDE4APDE4BPDE4C | |
| SCHEMBL28460689 | 0.91 | DHODH (0.40) | DHODHMALT1S1PR1S1PR3PDE4A | |
| SCHEMBL29019794 | 0.90 | DHODH (0.40) | DHODHMALT1TRPV1 | |
| SCHEMBL28451730 | 0.90 | DHODH (0.37) | DHODHMALT1EPHX2NTRK1 | |
| SCHEMBL14495255 | 0.88 | DHODH (0.39) | DHODHMALT1 | |
| SCHEMBL28455295 | 0.88 | DHODH (0.38) | DHODHMALT1TRPV1 | |
| SCHEMBL28460686 | 0.87 | DHODH (0.38) | DHODHMALT1TRPV1 | |
| SCHEMBL14495164 | 0.85 | DHODH (0.38) | DHODHMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116264894-A | Preparation and application of 1-pyridylpyrazole amide compound | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | claimed |
| CN-114516855-A | Preparation of pyridylpyrazole amide compounds and intermediates therefor | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-114516854-A | Preparation method of 1-pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-111662269-B | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2021-05-07 | — | — | CN | claimed |
| CN-111662269-A | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | claimed |
| CN-116264894-B | Preparation and application of 1-pyridylpyrazole amide compound | 湖南化工研究院有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-116264894-A | Preparation and application of 1-pyridylpyrazole amide compound | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-114516855-A | Preparation of pyridylpyrazole amide compounds and intermediates therefor | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-114516854-A | Preparation method of 1-pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-111662269-B | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-111662269-A | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | disclosed |