Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24397959 | 0.96 | DHODH (0.39) | DHODHMALT1EPHX2NTRK1 | |
| SCHEMBL28451756 | 0.92 | CHIA (0.36) | DHODHNTRK1 | |
| SCHEMBL28459476 | 0.90 | DHODH (0.38) | DHODHMALT1EPHX2NTRK1 | |
| SCHEMBL28455051 | 0.90 | DHODH (0.42) | DHODHMALT1EPHX2NTRK1 | |
| SCHEMBL28451020 | 0.86 | DHODH (0.38) | DHODH | |
| SCHEMBL24397793 | 0.86 | CHIA (0.39) | DHODHNTRK1 | |
| SCHEMBL28460725 | 0.86 | DHODH (0.38) | DHODH | |
| SCHEMBL24397797 | 0.86 | DHODH (0.37) | DHODHMALT1 | |
| SCHEMBL29181519 | 0.86 | DHODH (0.37) | DHODHMALT1 | |
| SCHEMBL29181560 | 0.86 | DHODH (0.37) | DHODHMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114516855-A | Preparation of pyridylpyrazole amide compounds and intermediates therefor | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-114516854-A | Preparation method of 1-pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-111662269-B | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-111662269-A | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | disclosed |