Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24397797 | 0.93 | DHODH (0.37) | DHODHMALT1CNR2ALDH1A1AVPR1A | |
| SCHEMBL28450734 | 0.93 | DHODH (0.36) | DHODHMALT1CNR2ALDH1A1AVPR1A | |
| SCHEMBL28455295 | 0.92 | DHODH (0.38) | DHODHMALT1CNR2TRPV1AVPR1A | |
| SCHEMBL28460686 | 0.91 | DHODH (0.38) | DHODHMALT1TRPV1AVPR1A | |
| SCHEMBL28455051 | 0.90 | DHODH (0.42) | DHODHMALT1TRPV1 | |
| SCHEMBL28455369 | 0.89 | DHODH (0.37) | DHODHMALT1CNR2CNR1 | |
| SCHEMBL14495164 | 0.88 | DHODH (0.38) | DHODHMALT1TRPA1 | |
| SCHEMBL28460689 | 0.88 | DHODH (0.40) | DHODHMALT1CNR2ALDH1A1CNR1 | |
| SCHEMBL28458430 | 0.88 | DHODH (0.40) | DHODHMALT1 | |
| SCHEMBL29181519 | 0.86 | DHODH (0.37) | DHODHMALT1CNR2TRPV1AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116264894-A | Preparation and application of 1-pyridylpyrazole amide compound | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | claimed |
| CN-116264894-B | Preparation and application of 1-pyridylpyrazole amide compound | 湖南化工研究院有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-116264894-A | Preparation and application of 1-pyridylpyrazole amide compound | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | disclosed |