Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160022 | 0.92 | FAAH (0.53) | CNR1FAAHCASP2ALDH1A1DNM1 | |
| SCHEMBL10448948 | 0.92 | FAAH (0.53) | CNR1FAAHCASP2ALDH1A1DNM1 | |
| SCHEMBL13375742 | 0.89 | CASP2 (0.63) | CNR1FAAHCASP2ALDH1A1DNM1 | |
| SCHEMBL24380513 | 0.88 | CNR1 (0.46) | CNR1FAAHCASP2ALDH1A1DNM1 | |
| SCHEMBL16154442 | 0.88 | KMT2A (0.46) | CNR1FAAHCASP2ALDH1A1DNM1 | |
| SCHEMBL13374398 | 0.88 | TSHR (0.48) | CNR1FAAHCASP2ALDH1A1DNM1 | |
| SCHEMBL13375747 | 0.87 | CASP2 (0.67) | FAAHCASP2ALDH1A1DNM1NAAA | |
| SCHEMBL13375743 | 0.86 | CASP2 (0.55) | CNR1FAAHCASP2ALDH1A1DNM1 | |
| SCHEMBL13374393 | 0.86 | CASP2 (0.48) | CNR1FAAHCASP2ALDH1A1DNM1 | |
| SCHEMBL13617197 | 0.85 | FAAH (0.56) | CNR1FAAHCASP2ALDH1A1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459004-B | Apelin receptor (APJ) agonists and uses thereof | 研究三角协会 | 2020-09-15 | — | — | CN | claimed |