Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220662 | 0.70 | CYP19A1 (0.50) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL31511551 | 0.70 | TSHR (0.38) | MMP13ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL188183 | 0.70 | TSHR (0.38) | MMP13ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL724151 | 0.69 | — | — | |
| SCHEMBL3614808 | 0.68 | ALDH1A1 (0.42) | MMP13MMP2MMP9MMP8ALDH1A1 | |
| SCHEMBL30413609 | 0.68 | ALDH1A1 (0.42) | MMP13MMP2MMP9MMP8ALDH1A1 | |
| SCHEMBL3293694 | 0.67 | ALDH1A1 (0.35) | ALDH1A1MAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL3293139 | 0.67 | CYP19A1 (0.52) | ALDH1A1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29452982 | 0.67 | HTR6 (0.33) | NQO2CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL28007719 | 0.67 | CYP19A1 (0.46) | ALDH1A1MAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732536-B | Synthesis method of aminopyridine compound | 凯莱英医药集团（天津）股份有限公司 | 2021-05-04 | — | — | CN | disclosed |
| CN-111732536-A | Synthesis method of aminopyridine compound | 凯莱英医药集团（天津）股份有限公司 | 2020-10-02 | — | — | CN | disclosed |