Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.33 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28460675 | 0.93 | DHODH (0.34) | DHODHPDE11ANAMPTCNR1CNR2 | |
| SCHEMBL28460686 | 0.93 | DHODH (0.38) | DHODHMALT1PDE11AAOC3 | |
| SCHEMBL29019794 | 0.89 | DHODH (0.40) | DHODHMALT1CNR1CNR2 | |
| SCHEMBL28456835 | 0.89 | DHODH (0.34) | DHODHHSP90AA1PDE11ANAMPTAOC3 | |
| SCHEMBL28460544 | 0.87 | HCRTR1 (0.35) | DHODH | |
| SCHEMBL28455371 | 0.87 | DHODH (0.35) | DHODHAOC3 | |
| SCHEMBL28458430 | 0.86 | DHODH (0.40) | DHODHMALT1NTRK1 | |
| SCHEMBL28456794 | 0.86 | DHODH (0.35) | DHODHAOC3 | |
| SCHEMBL28455051 | 0.85 | DHODH (0.42) | DHODHMALT1NTRK1 | |
| SCHEMBL28455295 | 0.85 | DHODH (0.38) | DHODHMALT1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116264894-A | Preparation and application of 1-pyridylpyrazole amide compound | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | claimed |
| CN-114516855-A | Preparation of pyridylpyrazole amide compounds and intermediates therefor | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-114516854-A | Preparation method of 1-pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-111662269-B | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2021-05-07 | — | — | CN | claimed |
| CN-111662269-A | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | claimed |
| CN-116264894-B | Preparation and application of 1-pyridylpyrazole amide compound | 湖南化工研究院有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-116264894-A | Preparation and application of 1-pyridylpyrazole amide compound | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-114516855-A | Preparation of pyridylpyrazole amide compounds and intermediates therefor | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-114516854-A | Preparation method of 1-pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-111662269-B | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-111662269-A | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | disclosed |