Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ME2 | P23368 | 1/20 | 0.39 |
| ▸ | ME1 | P48163 | 1/20 | 0.39 |
| ▸ | ME3 | Q16798 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369951 | 0.77 | AXL (0.44) | KMT2ATDP1GAAKDM4EMAPT | |
| SCHEMBL8304973 | 0.73 | KMT2A (0.42) | KMT2ATDP1GAAKDM4EMAPT | |
| SCHEMBL13808973 | 0.72 | CA12 (0.42) | GAAKDM4EMAPTMAPK1APP | |
| SCHEMBL5560822 | 0.68 | AXL (0.61) | KMT2ATDP1GAAKDM4EMAPT | |
| SCHEMBL14373829 | 0.68 | NOTUM (0.62) | KMT2ATDP1GAAKDM4EMAPT | |
| SCHEMBL8621001 | 0.67 | KMT2A (0.58) | KMT2ATDP1GAAKDM4EMAPT | |
| SCHEMBL22908613 | 0.65 | APP (0.71) | KMT2ATDP1GAAKDM4EMAPT | |
| SCHEMBL197522 | 0.63 | CA1 (0.79) | TDP1GAAKDM4EMAPTMAPK1 | |
| SCHEMBL6733562 | 0.63 | CA1 (0.79) | TDP1GAAKDM4EMAPTMAPK1 | |
| SCHEMBL9151672 | 0.63 | CA1 (0.79) | TDP1GAAKDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111742034-A | Use of caryophyllene-coated AIE nanodots with high nonradiative attenuation inhibition for enhancing cancer phototherapy in vivo | 香港科技大学 | 2020-10-02 | — | — | CN | disclosed |