Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30435417 | 1.00 | MEN1 (0.68) | MEN1KMT2AMAPTRECQLMAOA | |
| SCHEMBL30435353 | 0.96 | MEN1 (0.73) | MEN1KMT2AMAPTRECQLMAOA | |
| SCHEMBL28897418 | 0.91 | MEN1 (0.72) | MEN1KMT2AMAPTRECQLMAOA | |
| SCHEMBL30435008 | 0.91 | MEN1 (0.72) | MEN1KMT2AMAPTRECQLMAOA | |
| SCHEMBL30434922 | 0.89 | MEN1 (0.74) | MEN1KMT2AMAPTRECQLMAOA | |
| SCHEMBL28446516 | 0.88 | MAOA (0.55) | MEN1KMT2AMAPTRECQLMAOA | |
| SCHEMBL30434230 | 0.88 | MAOA (0.55) | MEN1KMT2AMAPTRECQLMAOA | |
| SCHEMBL28446530 | 0.87 | MEN1 (0.77) | MEN1KMT2AMAPTRECQLMAOA | |
| SCHEMBL30435155 | 0.82 | MAPT (0.84) | MEN1KMT2AMAPTRECQLMAOA | |
| SCHEMBL28440914 | 0.82 | MEN1 (0.70) | MEN1KMT2AMAPTRECQLMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423374-B | Dihydropyrazole sulfonamide compound and preparation method and application thereof | 合肥工业大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-111423374-A | Dihydropyrazole sulfonamide compound and preparation method and application thereof | 合肥工业大学 | 2020-07-17 | — | — | CN | disclosed |