Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28466821 | 0.91 | RAB9A (0.56) | RAB9ACYP1A2NPC1SMN1; SMN2LMNA | |
| SCHEMBL28899268 | 0.91 | RAB9A (0.55) | RAB9ACYP1A2NPC1SMN1; SMN2MAPT | |
| SCHEMBL28459622 | 0.87 | ALDH1A1 (0.53) | RAB9ACYP1A2NPC1SMN1; SMN2LMNA | |
| SCHEMBL28455179 | 0.84 | ALDH1A1 (0.51) | RAB9ACYP1A2NPC1SMN1; SMN2LMNA | |
| SCHEMBL31504224 | 0.84 | MAPT (0.69) | RAB9ACYP1A2NPC1SMN1; SMN2LMNA | |
| SCHEMBL22495388 | 0.84 | MAPT (0.69) | RAB9ACYP1A2NPC1SMN1; SMN2LMNA | |
| SCHEMBL28899266 | 0.83 | ALDH1A1 (0.49) | RAB9ACYP1A2NPC1SMN1; SMN2LMNA | |
| SCHEMBL28456597 | 0.80 | PPARG (0.59) | RAB9ACYP1A2NPC1SMN1; SMN2LMNA | |
| SCHEMBL2169030 | 0.79 | MAPT (0.78) | RAB9ACYP1A2NPC1SMN1; SMN2LMNA | |
| SCHEMBL108756 | 0.78 | CYP1A2 (0.58) | RAB9ACYP1A2NPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511732-A | Radiolabelled compounds | 豪夫迈·罗氏有限公司 | 2020-08-07 | — | — | CN | claimed |
| CN-111511732-A | Radiolabelled compounds | 豪夫迈·罗氏有限公司 | 2020-08-07 | — | — | CN | disclosed |