Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22492326 | 0.71 | F12 (0.45) | F12F2 | |
| SCHEMBL28304605 | 0.71 | DRD4 (0.37) | — | |
| SCHEMBL22492369 | 0.71 | F12 (0.43) | F12F2 | |
| SCHEMBL28280853 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL29663637 | 0.69 | IDO1 (0.49) | — | |
| SCHEMBL8699708 | 0.69 | IDO1 (0.49) | — | |
| SCHEMBL9159890 | 0.69 | IDO1 (0.49) | — | |
| SCHEMBL782544 | 0.69 | IDO1 (0.49) | — | |
| SCHEMBL13229169 | 0.68 | KMT2A (0.38) | — | |
| SCHEMBL28787918 | 0.68 | SRD5A1 (0.41) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111670034-A | Pyranopyrazoles and pyrazolopyridines immunomodulators for the treatment of autoimmune diseases | 洛克菲勒大学 | 2020-09-15 | — | — | CN | disclosed |