Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7051130 | 0.88 | FAAH (0.41) | FAAHKDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL468002 | 0.81 | — | — | |
| Allylamine SCHEMBL10873683 | 0.79 | ALDH1A1 (0.41) | ALDH1A1ADH1BADH1AADH7 | |
| Trifluoroacetic Acid SCHEMBL7743954 | 0.79 | KDM4E (0.39) | FAAHKDM4EALDH1A1SMN1; SMN2POLB | |
| Ammonia Solution, Strong SCHEMBL7864442 | 0.79 | — | — | |
| Bromide SCHEMBL30721655 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL5383422 | 0.79 | — | — | |
| Water SCHEMBL2877037 | 0.79 | — | — | |
| Glycine SCHEMBL5985162 | 0.78 | GLRA1 (0.43) | GLRA1SLC6A9OR51E2KDM4EALDH1A1 | |
| Allylamine SCHEMBL6560144 | 0.77 | MAPT (0.35) | FAAHALDH1A1POLBPAOXLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115918670-A | Surface cleaning disinfectant and preparation method and application thereof | 广东环凯生物技术有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-111518625-A | Acidic cleaning agent and preparation method and application thereof | 广东环凯生物技术有限公司 | 2020-08-11 | — | — | CN | disclosed |