Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.71 |
| ▸ | TP53 | P04637 | 7/20 | 0.71 |
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.71 |
| ▸ | CSNK2B | P67870 | 6/20 | 0.71 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | CASP1 | P29466 | 2/20 | 0.69 |
| ▸ | CASP7 | P55210 | 2/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | RET | P07949 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659883 | 0.86 | MAPT (0.71) | MAPTTP53CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL7457890 | 0.84 | TP53 (0.72) | MAPTTP53KDM4EMEN1KMT2A | |
| SCHEMBL25209431 | 0.84 | MAPT (0.57) | MAPTTP53CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL4650064 | 0.83 | MAPT (1.00) | MAPTTP53CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6770344 | 0.83 | MAPT (0.67) | MAPTTP53CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5138212 | 0.82 | MAPT (1.00) | MAPTTP53CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL30667444 | 0.82 | MAPT (1.00) | MAPTTP53CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL4648920 | 0.81 | CSNK2A2 (1.00) | MAPTTP53CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL17353581 | 0.81 | MAPT (0.72) | MAPTTP53CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL31356554 | 0.81 | CSNK2A2 (1.00) | MAPTTP53CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111751465-B | Rapid quantitative screening method and application of liquorice antioxidant active ingredients | 山东大学第二医院 | 2022-01-11 | — | — | CN | disclosed |
| CN-111751465-A | Rapid quantitative screening method and application of liquorice antioxidant active ingredients | 山东省中医药研究院 | 2020-10-09 | — | — | CN | disclosed |