SCHEMBL31356554

SCHEMBL31356554

COc1ccc(-c2oc3ccc(C)cc3c(=O)c2O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 4/20 1.00
CSNK2B P67870 4/20 1.00
CSNK2A1 P68400 4/20 1.00
MAPT P10636 8/20 0.76
TP53 P04637 6/20 0.76
RXFP1 Q9HBX9 2/20 0.76
SMN1; SMN2 Q16637 1/20 0.76
KDM4E B2RXH2 5/20 0.73
CYP3A4 P08684 4/20 0.73
ALDH1A1 P00352 3/20 0.73
MEN1 O00255 3/20 0.73
KMT2A Q03164 3/20 0.73
CASP1 P29466 2/20 0.73
CASP7 P55210 2/20 0.73
HSD17B10 Q99714 3/20 0.70
HPGD P15428 1/20 0.70
POLB P06746 1/20 0.70
MAOB P27338 1/20 0.65
ACHE P22303 2/20 0.65
BACE1 P56817 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4648920 1.00 CSNK2A2 (1.00) CSNK2A2CSNK2BCSNK2A1MAPTTP53
SCHEMBL4650608 0.91 CSNK2A2 (0.82) CSNK2A2CSNK2BCSNK2A1MAPTTP53
SCHEMBL17786466 0.86 CSNK2A2 (0.75) CSNK2A2CSNK2BCSNK2A1MAPTTP53
SCHEMBL12941170 0.86 CSNK2A2 (0.75) CSNK2A2CSNK2BCSNK2A1MAPTTP53
SCHEMBL5043660 0.86 CSNK2A2 (0.75) CSNK2A2CSNK2BCSNK2A1MAPTTP53
SCHEMBL7124716 0.85 CSNK2A2 (0.74) CSNK2A2CSNK2BCSNK2A1MAPTTP53
SCHEMBL30667444 0.85 MAPT (1.00) CSNK2A2CSNK2BCSNK2A1MAPTTP53
SCHEMBL5138212 0.85 MAPT (1.00) CSNK2A2CSNK2BCSNK2A1MAPTTP53
SCHEMBL30807197 0.84 CYP3A4 (0.87) CSNK2A2CSNK2BCSNK2A1MAPTTP53
SCHEMBL12590664 0.84 MAPT (0.84) CSNK2A2CSNK2BCSNK2A1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250368629-A1 FLAVONOID COMPOUNDS AND METHODS AND MATERIALS FOR USING FLAVONOID COMPOUNDS TO TREAT FIBROTIC CONDITIONS MAYO FOUND MEDICAL EDUCATION & RES (US) 2025-12-04 US disclosed
CN-119365193-A Flavonoid compounds and methods and materials for treating fibrotic disorders using flavonoid compounds 梅约医学教育与研究基金会 2025-01-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368629-A1 FLAVONOID COMPOUNDS AND METHODS AND MATERIALS FOR USING FLAVONOID COMPOUNDS TO TREAT FIBROTIC CONDITIONS FABP1, FN1, MMP1 CSNK2A2 4537/4885CSNK2B 4384/4885CSNK2A1 4564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.