Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 12/20 | 0.57 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.57 |
| ▸ | F11 | P03951 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2415330 | 0.98 | LPL (0.59) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL24336324 | 0.86 | LIPG (0.57) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL26983231 | 0.83 | LPL (0.54) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL14790147 | 0.82 | LPL (0.61) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL24336012 | 0.81 | LIPG (0.65) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL28366112 | 0.81 | LIPG (0.59) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL30289570 | 0.79 | LPL (0.57) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL2319123 | 0.79 | LIPG (0.57) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL23031440 | 0.79 | LIPG (0.62) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL2574495 | 0.78 | LPL (0.65) | LPLLIPGF11F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655681-A | Heterocyclylamino-substituted triazoles as modulators of Rho-associated protein kinase | 莱德克斯制药公共有限公司 | 2020-09-11 | — | — | CN | disclosed |