Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 3/20 | 0.37 |
| ▸ | JAK1 | P23458 | 6/20 | 0.35 |
| ▸ | NAMPT | P43490 | 8/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21894615 | 0.87 | JAK1 (0.47) | JAK1NAMPT | |
| SCHEMBL21796952 | 0.80 | RXRA (0.44) | RXRARXRBRXRGATRJAK1 | |
| SCHEMBL23478560 | 0.80 | RXRA (0.44) | RXRARXRBRXRGATRJAK1 | |
| SCHEMBL21894614 | 0.79 | RXRA (0.35) | RXRARXRBRXRGATR | |
| SCHEMBL21796778 | 0.78 | RXRA (0.50) | RXRARXRBRXRGNAMPT | |
| SCHEMBL21796566 | 0.78 | RXRA (0.42) | RXRARXRBRXRGATRJAK1 | |
| SCHEMBL30811759 | 0.77 | RXRA (0.47) | RXRARXRBRXRGATR | |
| SCHEMBL21894611 | 0.74 | CDK9 (0.35) | RXRARXRBRXRGATRJAK1 | |
| SCHEMBL23779872 | 0.74 | JAK1 (0.43) | JAK1 | |
| SCHEMBL25413737 | 0.73 | RXRA (0.44) | RXRARXRBRXRGATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943890-B | Pharmaceutical compounds | 艾欧米制药有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-111943890-A | Pharmaceutical compounds | 艾欧米制药有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-107108556-B | Pharmaceutical compounds | 艾欧米制药有限公司 | 2020-09-29 | — | — | CN | disclosed |