SCHEMBL28458338

SCHEMBL28458338

C=C(C(=O)OC)C(OC)C(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.36
CA14 Q9ULX7 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL275279 0.77 SMN1; SMN2 (0.48) ALDH1A1SMN1; SMN2CA14TSHR
SCHEMBL6559975 0.76 SMN1; SMN2 (0.39) ALDH1A1SMN1; SMN2CA14
SCHEMBL10761672 0.74 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2CA14TSHR
SCHEMBL14749828 0.74 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2CA14TSHR
SCHEMBL14696842 0.73 ALDH1A1 (0.48) ALDH1A1
SCHEMBL15546527 0.73 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2CA14TSHR
SCHEMBL10720609 0.73 SMN1; SMN2 (0.36) ALDH1A1SMN1; SMN2CA14TSHR
SCHEMBL3005395 0.72 SMN1; SMN2 (0.48) ALDH1A1SMN1; SMN2CA14TSHR
SCHEMBL9867193 0.71 SMN1; SMN2 (0.39) ALDH1A1SMN1; SMN2CA14
SCHEMBL3909058 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115772110-A Method for preparing potassium ion competitive retarder non-surazan intermediate 沈阳药科大学 2023-03-10 CN disclosed
CN-111533729-B Tetrazole-substituted quinolinone derivative and preparation method and application thereof 盐城工学院 2022-07-26 CN disclosed
CN-111533729-A Tetrazole-substituted quinolinone derivative and preparation method and application thereof 盐城工学院 2020-08-14 CN disclosed