Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29842808 | 0.90 | L3MBTL1 (0.52) | L3MBTL1HDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL29842630 | 0.90 | L3MBTL1 (0.52) | L3MBTL1HDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL28455069 | 0.90 | L3MBTL1 (0.52) | L3MBTL1HDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL17173854 | 0.87 | HDAC1 (0.64) | L3MBTL1HDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL4828082 | 0.84 | L3MBTL1 (0.57) | L3MBTL1HDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL15091424 | 0.83 | L3MBTL1 (0.59) | L3MBTL1HDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL18549296 | 0.82 | HDAC3 (0.56) | L3MBTL1HDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL18549297 | 0.82 | HDAC3 (0.56) | L3MBTL1HDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL18549194 | 0.81 | PKM (0.52) | L3MBTL1HDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL18549196 | 0.81 | PKM (0.52) | L3MBTL1HDAC1HDAC3HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111662288-B | Small molecule compound for inhibiting AKT and STAT3 activity and application thereof | 徐州医科大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-111662288-A | Small molecular compound for inhibiting AKT and STAT3 activities and application thereof | 徐州医科大学 | 2020-09-15 | — | — | CN | disclosed |