SCHEMBL28458480

SCHEMBL28458480

NC(=O)c1cccc(N(Cc2ccccc2)Cc2ccccc2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.65
CRHBP P24387 1/20 0.59
CRHR2 Q13324 1/20 0.59
KMT2A Q03164 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
MEP1B Q16820 1/20 0.48
NR3C1 P04150 1/20 0.48
MEN1 O00255 1/20 0.47
PARP1 P09874 6/20 0.47
TSHR P16473 2/20 0.47
POLB P06746 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAPT P10636 1/20 0.47
CYP2C19 P33261 1/20 0.47
RECQL P46063 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
PLA2G10 O15496 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6952400 0.87 PTPN1 (0.68) PTPN1CRHBPCRHR2KMT2AL3MBTL1
SCHEMBL22658227 0.84 CRHBP (0.68) PTPN1CRHBPCRHR2KMT2AL3MBTL1
SCHEMBL3957425 0.82 TSHR (0.58) PTPN1CRHBPCRHR2KMT2AL3MBTL1
SCHEMBL12580733 0.81 PTPN1 (0.55) PTPN1CRHBPCRHR2KMT2AL3MBTL1
SCHEMBL12641426 0.81 PTPN1 (0.55) PTPN1CRHBPCRHR2KMT2AL3MBTL1
SCHEMBL7403019 0.81 PTPN1 (0.70) PTPN1CRHBPCRHR2KMT2AL3MBTL1
SCHEMBL21377435 0.80 PTPN1 (0.64) PTPN1CRHBPCRHR2KMT2AL3MBTL1
SCHEMBL6981412 0.80 PTPN1 (0.53) PTPN1CRHBPCRHR2KMT2AL3MBTL1
SCHEMBL6943441 0.79 PTPN1 (1.00) PTPN1CRHBPCRHR2KMT2AL3MBTL1
SCHEMBL11228424 0.79 PTPN1 (0.67) PTPN1CRHBPCRHR2KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109232649-B Tetrazole urease inhibitor type feed additive and preparation method thereof 北京绿摇饲料科技有限公司 2020-08-25 CN claimed
CN-109232646-B Triazole urease inhibitor type feed additive and preparation method thereof 赣州澳德饲料科技有限公司 2020-08-21 CN claimed
CN-109232649-B Tetrazole urease inhibitor type feed additive and preparation method thereof 北京绿摇饲料科技有限公司 2020-08-25 CN disclosed
CN-109232646-B Triazole urease inhibitor type feed additive and preparation method thereof 赣州澳德饲料科技有限公司 2020-08-21 CN disclosed